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What is HMB?

HMB or Beta-Hydroxy Beta-methylbutyrate (also shown as -hydroxy -methylbutyrate monohydrate) is a byproduct of the normal breakdown of the amino acid Leucine. It is therefore a metabolite of the essential amino acid - Leucine. HMB is produced in our body from the proteins in our diet and is also consumed in small amounts from the foods we eat.

What can HMB do for me?

Studies have shown that HMB supplementation can do the following:

  • Increase Muscle Mass
  • Decrease Body Fat
  • Increase VO2 max and Endurance

How does HMB produce all these positive effects?

HMB helps slow down a phenomenon known as proteolysis, which is the natural process of breaking down muscle that occurs especially after strenuous activity. It appears that HMB supplementation has a protective effect on muscle and may help the body get a head start on the recovery process by minimizing the amount of "muscle damage" and ensuing protein degradation after exercise. It is theorized that HMB is a building block for intra-muscular cholesterol, which your muscle needs after vigorous exercise for repair and growth.

In simpler terms, HMB allows the body to stay in an anabolic state longer and this allows the body to build more muscle.

Iowa State University first pioneered the use of HMB as a supplement for cattle. They found that by giving cattle HMB the cattle increased muscle mass and decreased body fat. After this they decided to conduct tests on humans and the results were very positive.

The Iowa State study consisted of 40 men who did 4 weeks of weight training, 3 times a day. One group received 3 grams of HMB a day. The other group received a placebo. After 4 weeks, the HMB group showed a greater increase in muscle, lost more fat and were stronger than the placebo group.

Are there any other studies on HMB?

Yes there have been numerous university and peer-reviewed studies done on HMB. Over twelve years, researchers have found that HMB has numerous beneficial effects, including producing better results from intense exercise. The list of HMB clinical studies is continually growing. Currently there are about 11 human clinical studies completed, many of which have been published as peer-reviewed papers, and there are still more ongoing studies with HMB. Only creatine has more studies published than HMB.

Click Here for HMB Studies

What will HMB supplements do for me?

It will do as much as you want it to; the harder you work, the more effect you will get. Studies have shown that HMB supplementation can do the following:

  • Increase Muscle Mass and Strength (twice the gain from exercise alone)
  • Decrease Body Fat (also twice the loss of exercise alone)
  • Decrease Muscle Damage (less soreness)

Who should take HMB supplements?

Before taking any supplement you should always consult with your doctor. If you perform any type of serious workout you may want to consider taking a HMB supplement. The more intense your workout, the more benefit you will get from HMB.

The following people should NOT take HMB:
- Pregnant women
- Women who are breast feeding
- Anyone who has been advised not to by a doctor

If you are on any medications or have a medical condition, you should always consult with your Doctor before taking any dietary supplement.

Does HMB work for women and older adults?

Yes, published research results show that women and older adults who take supplemental HMB and exercise have enhanced strength and increased fat loss as well.

What will HMB do for runners or cyclists that don't want to bulk-up?

Research has shown that HMB increases VO2 max (maximal oxygen consumption), which is an indicator of endurance capacity. HMB has also been shown to minimize muscle damage and soreness associated with prolonged/strenuous endurance exercise.

How long does it take to see effects from HMB?

Studies show that measurable increases in strength and lean body mass can occur in only a couple of weeks, however, it will most likely take three or four weeks to produce results that will also be noticed by others.

How much HMB should I take?

Most studies have shown positive results with 3 grams a day for average individuals. It is best to split it into three 1 gram servings, spread throughout the day. If you weigh less than 125 lbs, you may want to try 2 grams a day. If you weigh over 225 lbs you may want to use 4 grams a day.

Can I take HMB with other sports supplements?

As always you should consult with your Doctor before taking any new supplements. HMB is commonly used with other sports supplements like creatine, glutamine and whey protein. One of the more popular stacks is creatine and HMB. Creatine gives you the energy to build more muscle mass and HMB makes sure that your body is in an anabolic muscle building state. In addition, recent research shows that HMB combined with creatine produces greater results than either HMB or creatine alone.

Are there any negative side effects to HMB?

Extensive clinical studies have been conducted to specifically evaluate the safety of HMB and no negative side effects have been recorded in both men and women whether young or elderly. A summary of the effects of HMB on hematology, emotional profile and adverse effects as measured in 9 clinical studies showed only positive effects on cholesterol (7% decrease) and blood pressure (4.4 mm of Hg decrease).

How can I tell if the HMB is a licensed product?

MTI holds the use patents on HMB. Currently all genuine sources of HMB are required to carry one or more of the following Patent Numbers on the label: 4,992,470, 5,348,979, 5360,613, or 6,031,000. If at least one of these patent numbers is not on the package, it is likely not HMB. MTI takes patent issues very seriously. In combination with Iowa State University, MTI has filed numerous lawsuits against infringing companies. MTI's patent positions are very strong and they will continue to vigorously defend these patents worldwide.

Are there any negatives to HMB?

Probably the biggest problem with HMB is the cost. Because the process to make HMB is complicated, it is a relatively expensive supplement. HMB is not as cheap as Creatine or Whey Protein supplements, but it is effective.

Questions? Email us at questions @ powersupplements.com

Copyright 2007, Power Discovery, LLC
Please consult with a health care professional before starting any supplementation program. The information contained on this site is general in nature and PowerSupplements, LLC does not take any responsibility for any errors that may appear. PowerSupplements, LLC has made every attempt to make the information as accurate as possible, however, we do not warrant its accuracy. Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult with your professional health care provider before changing any medication.

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